Study of pulmonary hypertension in post-COVID-19 patients by transthoracic echocardiography

BackgroundA devastating medical disorder, the coronavirus pandemic infection (COVID-19), produced by the coronavirus 2 (SARSCoV-2), is primarily characterized by severe pneumonia. Pulmonary hypertension (PH), which may cause right ventricular (RV) involvement and dysfunction, can occur as a result of lung parenchymal injury and disturbed pulmonary circulation. Transthoracic echocardiography (TTE) is a very reliable noninvasive approach to determining the severity of PH. Similar to that, thorax computer tomography (TCT) can effectively detect the severity of lung damage during the acute phase of a COVID-19 infection.AimsThe goal of this research is to examine PH and altered right ventricular function by TTE in post-COVID-19 cases.Patients and methodsThis retrospective case-control study was conducted at Tanta Chest University Hospital, Tanta, Egypt. The study started from October 2021 to September 2022 on 50 post-COVID-19 cases with one or more clinical manifestations of PH. These cases underwent TTE (group I showed normal PAP "control group," groups II & III with PH further subdivided according to PaO2).ResultsRisk factors of age, BMI, diabetes mellitus, and smoking were substantially raised in group III, but sex and hypertension were insignificant. Symptoms of chest pain, dyspnea, and palpitation were worse in group III. Levels of LDH, d-dimer, ESR, and serum bilirubin were substantially increased in group III in comparison to the other groups. Post-COVID-19-associated lung fibrosis and embolism were higher in group III. Mean values of estimated systolic pulmonary artery pressure (esPAP) and right atrial and right ventricular diameters were substantially increased in groups III and II in comparison to group I. Mean values of RV-GLS and TAPSE were lower in groups III and II in comparison to group I. FEV1, FVC, PEFR, and FEF25-75% percentage of the predicted were significantly low in groups II and III. FEV1/FVC ratio was substantially lower in group II in comparison to groups I and III.ConclusionsThe incidence of pulmonary hypertension in post-COVID-19 patients with suspected manifestations of PH is 70%. Increased age, BMI, DM, smoking, decreased PaO2, increased CORADS score, and abnormal spirometry are risk factors for PH in post-COVID-19 patients. Patients with post-COVID-19 PH stay more either in ICU or ward.

Community-Based Seroprevelance of SARS-CoV-2 in Saudi Arabia.

Introduction  The new coronavirus disease 2019 (COVID-19) is a major global concern. Due to the number of asymptomatic cases that go untested, the actual proportion of those who have been infected is likely to be higher than the reported prevalence. Thus, investigating the exact proportion of those who developed antibodies against the virus through serological surveys is crucial to identify the immune status of the population and direct public health decisions accordingly. Objectives The aim of this study is to estimate the seroprevalence of SARS-CoV-2 in the community and to describe the epidemiological characteristics of the discovered cases. Methods Between July and October 2020, a cross-sectional sero-survey was conducted including a total of 15,873 serum samples collected from seven regions within the kingdom. Using a multistage convenient sampling, people were invited to participate in an interviewer-administrated questionnaire. Afterward, blood samples were collected and seroprevalence was determined using the SARS-CoV-2 virus IgG/IgM antibody detection kits (ELISA). A p-value of <0.05 and 95% CI were used to report the significance. Results The overall seroprevalence of SARS-CoV-2 in the sample was 17.0%, and Makkah region constituted the highest number of reactive cases (33.3%). There was a significant association between all comorbidities and having symptoms except for diabetes. In addition, age, education, nationality, and region were all significant predeterminants of sero-result. Also, contact with a confirmed or suspected case increased the risk of being seropositive by nearly 1.5 times. Conclusion This study estimated the national seroprevalence of SARS-CoV-2 in Saudi Arabia to be 17%. At the time of this study, most of the population did not have the SARS-CoV-2 specific antibodies. This suggests that the population is still below the threshold of herd immunity and emphasizes the importance of mass vaccination programs and abiding by recommended prevention precautions.

Visualization Techniques in Healthcare Applications: A Narrative Review.

Nowadays, healthcare management systems are adopting various techniques that facilitate the achievement of the goals of evidence-based medical practice. This review explores different visualization techniques and their importance in healthcare contexts. We performed a thorough search on databases such as the SLD portal, PubMed, and Google Scholar to obtain relevant studies. We selected recent articles published between 2018 and 2021 on visualization techniques in healthcare. The field of healthcare generates massive volumes of data that require visualization techniques to make them easily comprehensible and to guide their efficient presentation. Visualization in healthcare involves the effective presentation of information through graphics, images, and videos. Big data systems handle a massive amount of information and require visualization techniques to present it in a comprehensible manner. The significance of visualization techniques in healthcare is not confined to healthcare practitioners and healthcare management but encompasses all the stakeholders; patients can benefit from the visualization of his/her data for a better understanding of their condition. In short, visualization techniques have demonstrated their benefits in the healthcare sector and can be extended to the payer and the patient. They have also had a positive impact on the quality of the healthcare provided as well as patient safety.

COVID-19 Diagnosis System using SimpNet Deep Model

After the outbreak of COVID-19, immediately it converted from epidemic to pandemic. Radiologic images of CT and X-ray have been widely used to detect COVID-19 disease through observing infrahilar opacity in the lungs. Deep learning has gained popularity in diagnosing many health diseases including COVID-19 and its rapid spreading necessitates the adoption of deep learning in identifying COVID-19 cases. In this study, a deep learning model, based on some principles has been proposed for automatic detection of COVID-19 from X-ray images. The SimpNet architecture has been adopted in our study and trained with X-ray images. The model was evaluated on both binary (COVID-19 and No-findings) classification and multi-class (COVID-19, No-findings, and Pneumonia) classification tasks. Our model has achieved an accuracy value of 98.4% for binary and 93.8% for the multi-class classification. The number of parameters of our model is 11 Million parameters which are fewer than some state-of-the-art methods with achieving higher results. © 2022 University of Baghdad. All rights reserved.

Telemedicine Patient Satisfaction and Cost: A Comparative Study in the COVID-19 Era.

INTRODUCTION: Telemedicine has the potential to enhance access to healthcare services across distances and this was of great value during the COVID-19 pandemic. However, concerns about user satisfaction in comparison to face-to-face (FTF) interaction remain inadequately addressed. OBJECTIVE: This study aimed to assess the impact of telemedicine technology from the patient perspective by comparing patient satisfaction and cost savings of follow-up visits through telemedicine with those of FTF clinical visits. METHODS: A cross-sectional study was conducted with two groups i.e., a telemedicine group and a control group that received FTF care at a tertiary hospital. RESULTS: This study demonstrated that the telemedicine group had patient satisfaction levels similar to those of the FTF clinical visit group, having a lower cost of care. Factors associated with patient satisfaction with telemedicine clinical care are identified and discussed. Both groups showed similar results in overall satisfaction with substantial cost savings for telemedicine patients.  Conclusion: Positive impacts of telemedicine technology from the patient perspective were seen and decision-makers must expand telemedicine efforts and continuously monitor patient perceptions toward telemedicine.

Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study.

There are limited data about neurological manifestations in pediatric COVID-19 patients from all over the world, including Saudi Arabia. This study was performed to identify characteristics of pediatric COVID-19 cases with neurologic involvement hospitalized at King Abdulaziz University Hospital (KAUH), Saudi Arabia. This retrospective cross-sectional study included hospitalized patients aged 0-19 years with confirmed SARS-CoV-2 from April 2020 to February 2022. The required data were retrieved from patients' medical records. Ninety-four cases were included. The median ages of the studied group, those with neurological manifestations, and those without neurologic manifestations, were 6.5, 11.0, and 5.0 years, respectively. Neurological manifestations occurred in 29 COVID-19 patients (30.9%) with headache and decreased consciousness being the most common recorded manifestations in 8.5% and 6.4% of patients, respectively. Specific neurological manifestations were rare, as only two infants developed encephalopathy with fatal outcome. Most patients with and without neurological manifestations survived. Neuroimaging abnormalities were detected in 8 cases with neurological manifestations. Neurological manifestations were common in 31% of hospitalized pediatric COVID-19 cases. However, most of the neurological manifestations were mild and nonspecific, with headache being the most common one. Specific neurological manifestations were rare; however, pediatric COVID-19 patients, particularly young infants, were at risk of developing severe encephalopathy with fatal outcome.

Delivering Future-Ready Financial Management Course for Non-finance Students Using Internet of Things (IoT)

It is evident that the impacts of COVID-19 crisis on education inevitably require a myriad of innovations on the delivery of conventional financial management courses in higher-educational institutions. The Future-Ready Financial Management Course (FRFMC) was one of a plethora of innovations that was developed to uncover the gap in the current curriculums. It also aims to cultivate and expand the abilities of students by enriching teaching contents and optimizing teaching methods through the Future-Ready Curriculum using a modified Attracting, Informing, Positioning and Delivering model. The development of FRFMC is extremely important as it can be used a means to attract non-finance students background to show interest in studying finance. Furthermore, the FRFMC dramatically changed the way higher-educational institutions, specifically educators in a financial management course to engage more efficiently and effectively with their new batches of digitally native and technologically savvy students. The reality is, many students are now on remote learning mode, highly depending on technology especially during the COVID-19 pandemic. While many students are considered sophisticated users of technology, few non-finance students are found struggling to learn the basics of finance for entrepreneurs. The FRFMC intends to cater to both groups of students. A number of 431 questionnaire surveys were collected among the non-finance student of Universiti Malaysia Kelantan and observations was adopted as the mechanisms to examine the students’ experience during the FRFMC implementation. The findings show that financial management courses can indeed be taught in a more innovative and effective way in order to draw the interest of non-finance students to take up more technical courses in the future. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

ECOVIDNET: Snapshot Ensembling Approach to Detect Coronavirus from Chest X-ray Images

To tackle the global pandemic of COVID-19, scholars are looking for accurate and efficient artificial intelligence approaches to screen the chest situation of the X-Ray images of the COVID-Affected people. Developing an accurate deep model is a goal which can be achieved through an ensemble of multiple deep models. Utilizing multiple networks boosts the performance and surpasses utilizing a single model classifier. However, it suffers from a high computational cost of training. To avoid this, we propose a novel deep network model namely ECOVIDNet. The proposed model is based on merging multiple model snapshots for final prediction at the cost of a single training run. The proposed scheme adopts EfficientNet through the transfer learning process with freezing all trainable layers and adding two fully connected layers at the end of the model. The model is trained on an X-ray image dataset with achieving an accuracy of 99.2%, 96.8% for binary (Normal vs COVID-19), and ternary (Normal vs COVID-19 vs Pneumonia) classifications. The model is evaluated with 5-fold cross-validation and obtained precision, sensitivity, and F1-score of 99.5%, 99.5, and 99.4%, respectively. Also, the proposed model yields 96.62% of precision, 96.5% of sensitivity, and 96.48% of F1-score in ternary classification. © 2022 IEEE.

Digital Leadership: Attributes of Modern Healthcare Leaders.

Background Living in the current digital era requires widespread adoption of information technology in the modern healthcare industry. Objective The current research aimed to study key attributes and behaviors related to successful leaders' need to achieve the vision and ensure successful health IT adoption. Methods A Delphi technique with three rounds was employed and guided by structured questions. Part of the study was conducted online due to COVID-19 guidelines on distancing norms and lockdown in some areas. The answers of the participants were evaluated on a five-point Likert scale. Results The findings showed that similar leadership qualities are required in the healthcare sector as well as other sectors. For digital innovations in the rapidly changing healthcare space, leaders need to play a more proactive role, be visionary and dynamic, and should lead by example to take the organization to the next level. Conclusions Leaders need to come out of their comfort zone, understand the fast-evolving scenario where outstanding leadership qualities are essential to prove their mettle, outshine others, and create a strong foundation for the adoption of modern, efficient, customized digital technology in the fast-growing healthcare sector.

Immunogenicity of The BNT162b2 COVID-19 mRNA and ChAdOx1 nCoV-19 Vaccines in Patients with Hemoglobinopathies.

INTRODUCTION: Studies assessing immune responses following Pfizer-BioNTech BNT162b2 mRNA COVID-19 (Pfizer) and ChAdOx1 nCoV-19 AZD1222 (AstraZeneca) vaccines in patients with hemoglobinopathy are non-existent in the literature despite being thought at high risk of infection. METHODS: Prospectively, we collected serum from patients with hemoglobinopathies at least 14 days post vaccine and measured neutralizing antibodies (nAb) in addition to binding antibodies using in-house assays. RESULTS: All 66 participants mounted a significant binding antibody response (100%), but nAbs were detected in (56/66) post-vaccine with a rate of 84.5%. Age, gender, vaccine type, spleen status, hydroxyurea use, and hyperferritinemia did not affect the rate significantly. While 23/32 (71.8%) patients receiving only one dose of the vaccine were able to mount a positive response, 33/34 (97.05%) of those who had two doses of any vaccine type had a significant nAbs response. Patients who had anti-nucleocapsid (N), signifying asymptomatic infection in the past, were able to produce nAbs (31/31). No nAbs were detected in 10/35 (28.5%) patients with no anti-N antibodies. CONCLUSION: Our results provide supportive data when advising patients with hemoglobinopathy to receive COVID-19 vaccines and ensure booster doses are available for better immunity. Whenever available, measurement of nAb is recommended.

Potential disruptive innovation: online learning of public speaking courses in higher education

Purpose The sudden pandemic of COVID-19 has caused disruptive innovation in all areas of business including education. Despite the educators' and students' acceptance and readiness in the new normal, the traditional face-to-face (FTF) public speaking has been shifted to online courses to suit the current needs. This study aims to examine whether there were differences between online and FTF pubic speaking in the students' anxiety level, speech performance, as well as their perceptions of the challenges in the implementation of online public speaking courses as a potential to disruptive innovation. Design/methodology/approach This pilot study was a mixed method research that involved a purposive sampling of two groups of 39 students in higher education. The instruments used were questionnaires of self-report anxiety, speech performance test and observation. Findings The findings show that the students preferred the traditional FTF rather than the online mode for public speaking courses. The challenges of internet connection and the lack of a live audience were their main concerns in online public speaking. It also provides a potential for disruptive innovation that could take into consideration of a live audience in university online courses. Originality/value This study provides the potential of public speaking course as a disruptive innovation. This brings implications for the innovators, marketers and educators to think of the online courses/programmes that can be best implemented while embracing the changes and the new normal of COVID-19 brings for student learning.

Safety of COVID-19 vaccines.

This study is aimed to identify the adverse effects associated with three types of coronavirus disease 2019 vaccines. Approximately 1736 individuals agreed to participate in this study. The participants involved in the study were individuals who had received the first dose or full course (two doses) of the vaccine at least 30 days before the survey. A direct and interactive web-based system interview with a paper and electronic version of the questionnaire was used for all participants. A total of 1736 randomized individuals were identified. The reactogenicity of the vaccines including pain, redness, urticaria, and swelling at the site of the injection was reported in 34.56% of the participants. Local site reaction was reported in more individuals who had Pfizer and AstraZeneca vaccines than those who received the Sinopharm vaccine. The systemic events were more common with AstraZeneca and Pfizer vaccines, symptoms reported were fatigue, body pain, headache, muscle pain, fever, and gastrointestinal side effects. There were no correlations between age or gender, and the duration of the adverse effects for the three vaccines. Swelling and severe allergic reaction of the eyelids, severe hypotension, generalized body aches, shortness of breath, weakness and numbness on the injected arm, acute hyperglycemia, severe chest pain, and fever more than 39°C were among the unusual signs and symptoms reported by the participants. Pfizer, AstraZeneca, and Sinopharm vaccines were found to be safe and Sinopharm vaccine showed a lower prevalence of adverse effects compared with the other vaccines. The duration and severity of adverse effects were not affected by age or gender. Unusual side effects should be closely monitored to establish determine they are linked to the immunization.

High seroprevalence of SARS-CoV-2 among high-density communities in Saudi Arabia.

BACKGROUND: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection had been investigated utilizing serology. MATERIALS AND METHODS: This community-based sero-survey was carried out in the neighborhoods of three cities in Saudi Arabia. RESULTS: Of 5629 participants, 2766 (49.1%) were women; and 2148 (38.1%) were 18-34 years of age, and 3645 (64.7%) were from South East Asia. Positive serology was seen in 2825 (50.2% (95% CI: 48.8-51.5%) for SARS-CoV-2 anti-S1 IgG antibodies by ECLIA. Being in the age category of 18-34 years and being from Eastern Mediterranean Region (country A) were associated with higher COVID-19 seropositivity with estimated odds ratio of 1.3 [95% CI 1.1-1.8] and 2.5 [95% CI 1.1.5-4.2] respectively. Gender, social status, education, nationality, symptoms, presence of comorbidities and activity style were positively associated with increased seropositivity. Factors associated negatively with the rate of seropositivity were higher education and having outdoor activity with estimated OR of 0.92 [95% CI 0.46-0.95] and 0.59 [95% CI 0.47-0.74], respectively. CONCLUSION: The study showed high seroprevalence of SARS-CoV-2 among high density population. Health education campaigns should target middle-aged, those with low education, those living in lower standards and indoor workers.

Low clinical utility of testing for anti-platelet factor 4 in asymptomatic individuals after ChAdOx1 nCoV-19 vaccine.

INTRODUCTION: The development of anti-platelet factor 4 (PF4) antibodies is linked to a rare thrombotic complication described now as vaccine-induced immune thrombotic thrombocytopenia (VITT). This clinical syndrome with thrombosis and thrombocytopenia was reported after exposure to the Oxford-AstraZeneca COVID-19 vaccine, ChAdOx1 nCoV-19 vaccine (AZD1222), and Ad26.COV2.S vaccine (Janssen/Johnson & Johnson). In the absence of the clinical features, the incidence of positive anti-PF4 antibodies in asymptomatic individuals post-vaccination is unclear. METHODS: The aim of this study was to evaluate the development of anti-PF4 antibodies in asymptomatic individuals 14-21 days after receiving the first dose of ChAdOx1 nCoV-19 vaccine (AZD1222) and BNT162b2 vaccine. Prospectively, we collected serum from individuals before and after ChAdOx1 nCoV-19 vaccine and BNT162b2 vaccine and measured anti-PF4 antibodies using the Asserachrom HPIA IgG ELISA (Stago, Asnieres, France). RESULTS: We detected positive anti-PF4 antibodies in 5 of 94 asymptomatic individuals post-vaccine with a rate of 5.3% with low titers (OD 0.3-0.7). Four of 5 individuals who tested positive after the vaccine had also positive anti-PF4 antibodies before the vaccine, which indicates that a majority of the positive results are due to preexisting anti-PF4 antibodies. We did not find a relation between the development of anti-PF4 antibodies and the immune response to the vaccine, status of prior COVID-19 infection, and baseline characteristics of participants. None of the participants developed thrombosis nor thrombocytopenia. CONCLUSION: Our results provide new evidence to guide the diagnostic algorithm of suspected cases of VITT. In the absence of thrombosis and thrombocytopenia, there is a low utility of testing for anti-PF4 antibodies.

How has the COVID-19 pandemic affect the rejection rates and repeat reasoning of digital radiography?

OBJECTIVES: To compare the digital radiology rejection rates and reasoning pre-COVID-19 (PC) and during COVID-19 (DC) from September 2019 to August 2020. METHODS: This record-base retrospective study where data were extracted from the radiography equipment (Carestream Health, Rochester, New York, USA) at the Department of Radiology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia over 12 months. The data were equally divided into PC and DC. RESULTS: The DC rejection rate decreased from PC by 2.6% with a significant p=0.00001. During COVID-19 there were 15,376 images of different body parts, versus 23,861 images during PC. Position errors were the main reasons for rejection for both PC (39.8%) and DC (42.7%), followed by technique errors (PC: 19.2%) (DC: 17.2%). CONCLUSION: Different sectors in hospitals were affected by COVID-19, including diagnostic radiology, in the positive direction. Thus, the DC rejection rate was markedly reduced compared with PC. This may be due to radiology technicians becoming more cautious in dealing with patients.

Primary Health Care in Pandemics: Barriers, Challenges and Opportunities

COVID-19 has become a major global public health threat. It started from Wuhan a province of China in December 2019 and has spread in every country of the globe with over 100 million people currently infected and over three million deaths as of May 2021. Nearly a year on, with many town and cities are in lockdown and with all public health measures to minimize transmission of the virus SARS-COV-2 and the scientific achievements with many vaccines developed in record time, the transmission in the second wave is still strong with new variants of the virus emerging. The pandemic has caused a serious impact on the economic, social, political, and cultural dynamics of people, globally. The majority of people with mild and moderate symptoms of COVID-19 seek primary care (PC) service as the entry point for getting medical intervention, reducing flow to hospital care. Currently, primary care settings are facing major challenges including lack of funds, poor infrastructure in some countries, and shortage of health care workers and equipment. Most, if not all primary care centers are not designed to separate people with the virus. The pandemic so far shows that strengthening primary care as the first point of contact with the health system is vital. The health systems of the future cannot be resilient without strong primary care for all, capable of meeting population health needs and aspiration for good health and well-being. [ABSTRACT FROM AUTHOR] Copyright of Middle East Journal of Family Medicine is the property of Medi+WORLD International Pty. Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Effects of antiviral drug therapy on dynamic thiol/disulphide homeostasis and nitric oxide levels in COVID-19 patients.

The novel coronavirus disease 2019 (COVID-19) has led to a serious global pandemic. Although an oxidative stress imbalance occurs in COVID-19 patients, the contributions of thiol/disulphide homeostasis and nitric oxide (NO) generation to the pathogenesis of COVID-19 have been poorly identified. Therefore, the aim of this study was to evaluate the effects of antiviral drug therapy on the serum dynamics of thiol/disulphide homeostasis and NO levels in COVID-19 patients. A total of 50 adult patients with COVID-19 and 43 sex-matched healthy control subjects were enrolled in this prospective study. Venous blood samples were collected immediately on admission to the hospital within 24 h after the diagnosis (pre-treatment) and at the 15th day of drug therapy (post-treatment). Serum native thiol and total thiol levels were measured, and the amounts of dynamic disulphide bonds and related ratios were calculated. The average pre-treatment total and native thiol levels were significantly lower than the post-treatment values (P < 0.001 for all). We observed no significant changes in disulphide levels or disulphide/total thiol, disulphide/native thiol, or native thiol/total thiol ratios between pre- and post-treatments. There was also a significant increase in serum NO levels in the pre-treatment values when compared to control (P < 0.001) and post-treatment measurements (P < 0.01). Our results strongly suggest that thiol/disulphide homeostasis and nitrosative stress can contribute to the pathogenesis of COVID-19. This study was the first to show that antiviral drug therapy can prevent the depletion in serum thiol levels and decrease serum NO levels in COVID-19 patients.

Improvement of professional commitments by strengthening achieving motivation in COVID-19 era

Professional commitment is a determination of one's attitude towards his job. Someone who has high professional commitment will develop a positive mindset. Someone who has a high professional commitment will have an identification of his work, is involved seriously and there are loyalty and positive understanding of his work. Many things can cause an increase in the professional commitment of a lecturer, one of which is achievement motivation. The aim of this research is to find an effort to increase the professional commitment of Islamic Private University lecturers in East Jakarta by identifying the strengths of the relationship between the achievement motivation variable and the commitment of the lecturer profession. The research method used was a survey method with a correlational approach. This study concludes that: There is a positive relationship between achievement motivation and professional commitment of lecturers through the regression equation Ŷ = 43.72 + 0.66X. The correlation coefficient is ry1 = 0.767 and the determination coefficient ry1² = 0.59. Thus it can be stated that the higher the achievement motivation of a lecturer, the higher the professional commitment of the lecturer.

Seroprevalence of antibodies to SARS-CoV-2 among blood donors in the early months of the pandemic in Saudi Arabia.

BACKGROUND: Serologic testing provides better understanding of SARS-CoV-2 prevalence and its transmission. This study was an investigation of the prevalence of antibodies to SARS-CoV-2 among blood donors in Saudi Arabia. OBJECTIVE: To estimate the seroprevalence of anti-SARS-CoV-2 antibodies among blood donors in Saudi Arabia during the early phase of the COVID-19 pandemic. METHODS: Serology results and epidemiological data were analyzed for 837 adult blood donors, with no confirmed SARS-CoV-2 infection, in Saudi Arabia from 20th to 25th May 2020. Seroprevalence was determined using electrochemical immunoassay to detect anti-SARS-CoV-2 antibodies. RESULTS: The overall seroprevalence of anti-SARS-CoV-2 antibodies was 1.4% (12/837). Non-citizens had higher seroprevalence compared with citizens (OR 13.6, p = 0.001). Secondary education was significantly associated with higher seroprevalence compared with higher education (OR 6.8, p = 0.005). The data showed that the highest seroprevalence was in Makkah (8.1%). Uisng Makkah seroprevalence as the reference, the seroprevalence in other areas was: Madinah 4.1% (OR 0.48, 95% CI 0.12-1.94), Jeddah 2.3% (OR 0.27, 95% CI 0.31-2.25), and Qassim 2.9 % (OR 0.34, 95% CI 0.04-2.89) and these were not statistically different from seroprevalence in the Makkah region. CONCLUSIONS: At the early months of the COVID-19 pandemic in Saudi Arabia, the seroprevalence of antibodies to SARS-CoV-2 among blood donors was low, but was higher among non-citizens. These findings may indicate that non-citizens and less educated individuals may be less attentive to preventive measures. Monitoring seroprevalence trends over time require repeated sampling.

Improving teacher health performance by strengthening organizational culture, personality and job satisfaction in covid-19 situation

The quality of teacher performance determines the quality of educational outcomes because the teacher is a figure who often interacts with students. The purpose of this study is to find ways to improve teacher performance, to examine organizational culture, personality and job satisfaction by identifying the direct influence of organizational culture on teacher performance, the direct effect of personality on teacher performance, the direct effect of job satisfaction on teacher performance, the direct effect of organizational culture on Job satisfaction, the direct effect of personality on job satisfaction and the direct effect of organizational culture on personality. The method used in this study was path analysis and SITOREM. In this study, there was a positive and significant direct effect between teacher performance with organizational culture, there was a positive and significant direct effect between teacher performance and personality, there was a positive and significant direct effect between teacher performance and job satisfaction, there was a positive and significant direct effect between organizational culture with personality, there was a positive and significant direct effect between personality and job satisfaction, and there was a positive and significant direct effect between organizational culture and personality.